Scientific News

  • Early Prognostic Factors for Reduced Survival in Autoimmune Hepatitis: A Systematic Review With Meta-Analysis

    Early cirrhosis detection and treatment response are crucial prognostic indicators in AIH, according to a recent systematic review.

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  • Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis

    A new multicenter study evaluates the prognostic value of liver stiffness measurement in PBC, highlighting its role in predicting hepatic decompensation independently of biochemical response.

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  • Fatigue in people with primary biliary cholangitis: a position paper from the European Reference Network for Rare Liver Diseases

    A systematic review by ERN RARE-LIVER outlines current evidence and clinical recommendations for managing fatigue in PBC patients.

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  • New R-LIVER Studies (BCS, PSVD, ALF & TPE) are now live!

    The ERN RARE-LIVER Registry has been expanded and is now available for new data entry.

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  • Efficacy and safety of infliximab in patients with Autoimmune Hepatitis

    This multicenter retrospective study evaluated infliximab in 42 patients with autoimmune hepatitis (AIH) unresponsive to standard therapies or with concurrent autoimmune diseases.

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  • Abdominal surgery in patients with chronic noncirrhotic extrahepatic portal vein obstruction: A multicenter retrospective study

    Information about the morbidity and mortality associated with abdominal surgery in patients with non-cirrhotic extrahepatic portal vein occlusion (EHPVO) is scarce.

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  • Longitudinal Evaluation of Individuals With Severe Alpha-1 Antitrypsin Deficiency (Pi∗ZZ Genotype) - New ERN Paper in Gastroenterology

    Non-invasive liver fibrosis surrogates are superior to lung parameter for prediction of organ-related outcomes. Liver disease progresses primarily in those individuals with risk factors/signs of liver injury.

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  • ERN RARE-LIVER/EASL Position Paper on Rare primary liver cancers

    In this position paper, an international panel of experts representing oncology, hepatology, pathology, radiology, surgery, and molecular biology has summarised the available information and evidence on the pathogenesis, diagnosis, and treatment of rare PLCs.

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  • New ERN RARE-LIVER Paper on PSVD - Journal of Hepatology

    Porto-sinusoidal vascular liver disorder (PSVD) is a rare liver condition that often leads to severe complications from portal hypertension and can reduce life expectancy.

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  • For Physicians: New ERN RARE-LIVER Survey on Alcohol Use

    ERN RARE-LIVER has constructed the survey “Counselling Young Adults With Liver Disease On Alcohol Use”. The survey will be open until 8 September, 2024. It consists of max. 10 pages and it will take 10 to 15 minutes to respond.

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Archive

Open Letter addressed to the European Commission
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Funding opportunity for clinical exchange
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3rd Wilson Aarhus Symposium 2-5 May 2024
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New CPSS Position Paper
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5th Autoimmune Hepatitis Research Workshop on 27 & 28 June 2024
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EU4Health funding opportunity for orphan medical devices
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New Video on how to use EBAR - The European Biliary Atresia Registry of the ERN RARE-LIVER
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Current transition management of adolescents and young adults with Liver Diseases: an ERN RARE-LIVER survey
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New Hepatic Alveolar Echinococcosis Working Group
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Biliary Atresia Register planned
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Young Investigator Workshop on Basic Science and Translational immunology in PSC
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Immuno-oncology (IO) in patients with autoimmune liver disease (AILD)
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Unconventional treatment of Autoimmune Hepatitis
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Rivaroxaban Prophylaxis in Non-cirrhotic Portal Vein Thrombosis
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Alpha1-antitrypsin deficiency (AATD) - associated liver disease
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Results of the EU survey on the availability of age-appropriate medication for children with autoimmune liver disease (AILD)
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Prevalence of COVID-19 in patients with autoimmune liver disease in Europe: a patient-oriented online survey performed by ERN RARE-LIVER
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SARS-CoV-2 in Pediatric Liver Transplant Recipients: The European Experience
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Mobile app requirements for patients with rare liver diseases: A single center survey for the ERN RARE-LIVER
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Quantification of polyreactive immunoglobulin G facilitates the diagnosis of autoimmune hepatitis.
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Incident Gallstones During Somatostatin Analog
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Study of ARO-AAT in Patients with Alpha-1 Antitrypsin Deficiency Associated Liver Dieseae (AATD)
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SARS-CoV-2 infection in patients with autoimmune hepatitis
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Adeno-associated virus (AAV) based gene therapy in Wilson's disease
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Effects of Primary Sclerosing Cholangitis on Risks of Cancer and Death in People With Inflammatory Bowel Diseases, Based on Sex, Race, and Age
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Cholangiocarcinoma 2020: the next horizon in mechanisms and management
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Second-line and Third-line therapy for Autoimmune Hepatitis A position statement from the European Reference Network on Hepatological Diseases and the International Autoimmune Hepatitis Group
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Study on liver involvement in mild alpha1-antitrypsin deficiency published in "Gastroenterology”
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A comprehensive characterization of liver involvement in alpha1-antitrypsin deficiency published in "Gastroenterology”
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Efficacy and safety of selective decontamination of the digestive tract (SDD)
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Rapid Response to Treatment of Autoimmune Hepatitis Associated With Remission at 6 and 12 Months
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High discontinuation rate of azathioprine in autoimmune hepatitis, independent of time of treatment initiation
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Cross-sectional screening study for Biliary Atresia (BA)
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Immune suppressed patients during the COVID 19 outbreak
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A retrospective study on cancer surveillance in patients with PSC
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Polycystic Kidney and Liver Disease
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Novel pharmacologic treatment approaches targeting fibrogenesis
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Alpha1-antitrypsin
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Optimal transplantation in paediatric rare liver diseases
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Disease activity and fibrosis in patients with AIH
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Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis
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