Abdominal surgery in patients with chronic noncirrhotic extrahepatic portal vein obstruction: A multicenter retrospective study

This multicenter retrospective study evaluates the outcomes of 76 patients with EHPVO undergoing abdominal surgery, and found that 37% experienced an unfavourable outcome defined as major bleeding, serious postoperative complications, portal hypertension–related events, or death. Risks were especially high in patients with a history of ascites or those undergoing surgeries other than cholecystectomy or abdominal wall procedures. Compared to 126 matched controls without EHPVO, these patients had significantly higher rates of major bleeding and portal hypertension–related complications. The study emphasizes the significant perioperative risks associated with EHPVO and provides information suggesting that while EHPVO remains a high-risk condition, certain surgical interventions may be safely considered with appropriate risk stratification.

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