Assistance Publique-Hôpitaux de Paris, Hôpital Beaujon



Contact Information for physicians and patients

Hôpital Beaujon
Service d’Hépatologie, Bâtiment Abrami – Secteur jaune – Porte 4
100, Boulevard du Général Leclerc 
+331 40 87 55 97 / +331 40 87 51 60

Particular rare liver disease expertise of the centre

Vascular liver diseases (VLD) :

  • Budd-Chiari syndrome (BCS)
  • Non-cirrhotic acute and chronic portal vein thrombosis (PVT),
  • Portal cavernoma or chronic non cirrhotic extrahepatic portal vein obstruction,
  • Extrahepatic portal vein obstruction (ehpvo) in cirrhosis
  • Veno occlusive disease (VOD),
  • Sinusoidal obstruction syndrome (SOS)
  • Idiopathic non-cirrhotic portal hypertension (INCPH),
  • Porto sinusoidal vascular disease,
  • Drug induced liver injury and vascular liver disease,
  • Ischemic cholangiopathy,
  • Congenital portosystemic shunts,
  • Pregnancy and vascular liver diseases,
  • Fontan related liver disease

Risk Factors for Vascular Liver Diseases 
Management and treatments for VLD:

  • Percutaneous liver biopsy
  • Transjugular liver biopsy
  • Hepatic hemodynamic studies
  • Direct transhepatic venography, 
  • Retrograde transjugular or transfemoral venography
  • Anticoagulation therapy in patients at risk for gastrointestinal bleeding related to portal hypertension
  • Percutaneous angioplasty and stenting 
  • Liver transplantation

French network competence center for Autoimmune and biliary diseases:

  • Primary Biliary Cholangitis (PBC, formerly Primary Biliary Cirrhosis)
  • Autoimmune Hepatitis (AIH)
  • Primary Sclerosing Cholangitis (PSC)
  • Alpha-1 Antitrypsin Liver Disease
  • Wilson’s Disease
  • LPAC syndrome

French network competence center for biliary atresia and intrahepatic cholestasis

  • Benign recurrent intrahepatic cholestasis
  • Familial progressive intrahepatic cholestasis Biliary Atresia
  • Choledochal Cyst, Alagille Syndrome

ERN Representatives

  • dr_audrey_payance.jpg

    Audrey Payancé

    Autoimmune and biliary diseases competence center coordinator

    Centre de référence des maladies vasculaires du foie (CRMVF)

  • dr_aur_lie_plessier_-_crmvf_coordinator.jpg

    Aurélie Plessier

    CRMVF coordinator and Biliary atresia and cholestatic liver diseases competence center coordinator

    Centre de référence des maladies vasculaires du foie (CRMVF)

ERN Team and Contact

  • Dr Odile GORIA
  • Dr Aurélie PLESSIER
  • Dr Audrey PAYANCE
  • Pr Pierre-Emmanuel RAUTOU
  • Pr Dominique VALLA
  • Nurse Coordinator – Mrs Marie SANTIN – marie.santin(at)
  • Assistant – Mrs Valérie de BREMAND – valerie.debremand(at)
  • Clinical Research Associate – Mr Kamal Zékrini – kamal.zekrini(at)

Centre information

The referral centre for vascular liver diseases in France, “centre de référence des maladies vasculaires du foie” (CRMVF), coordinates a national network for vascular liver diseases (32 local “centres de competence” and 1constitutive pediatrician liver centre), accredited by the French Ministry of Health in 2005. The CRMVF coordinated by Dr A Plessier is one of 4 centres of the french rare liver disease network called, “filière for rare liver disease“, FILFOIE, accredited in 2015, and one of the teams composing the academic department DHU “UNITY” (addressing the Unmet Needs through Innovation in gastroenterologyand hepatologY), accredited in 2014. 
CRMVF, a patient-centered care network, aims at offering the best possible management for patients with vascular liver disease, wherever they are living in France. A multidisciplinary team includes experts in vascular liver diseases including: hepatology and liver transplantation, diagnostic and interventional radiology, endoscopy, hematology, biochemistry, intensive care-anesthesiology, liver and gastrointestinal surgery. The aim is to offer expert management locally as much as possible. Only when necessary, (e.g. for technical procedures that cannot be performed otherwise), the patient is seen at CRMVF in Beaujon. This paradigm fosters the development of improved local management mostly through training and collaboration. 
CRMVF’s 2 additional aims are i) to share best practices, nationally and internationally, in the management of patients ii) to foster and expand clinical and translational research.
The centre is also a competence centre for autoimmune and biliary diseases coordinated by Dr A Payancé and biliary atresia and cholestatic liver diseases coordinated by Dr A Plessier.