Autoimmune Liver Diseases (AILD)

  • Autoimmune Hepatitis (AIH)

    Autoimmune hepatitis (AIH) is a rare autoimmune liver disease. The immune system of patients with AIH mistakenly targets the body’s own liver cells causing damage and inflammation. AIH can be diagnosed at any age and affects more females than males.…
  • Primary Biliary Cholangitis (PBC, formerly Primary Biliary Cirrhosis)

  • Sclerosing cholangitis

    • IgG4-related sclerosing cholangitis

    • Primary sclerosing cholangitis (PSC)

      Primary sclerosing cholangitis (PSC) is a rare, immune-mediated liver disease that leads to scarring in the bile ducts. This means that bile, which normally flows through the bile ducts into the intestines, can’t drain properly and it builds up in…

Metabolic, Biliary Atresia & Related Diseases

  • Alpha-1 Antitrypsin Deficiency (AATD)

    Alpha1-antitrypsin deficiency is an inborn genetic disorder that affects 1 in 2500 individuals. It increases susceptibility to lung disease in adults (emphysema), and liver disease in both children and adults. It is one of the main causes of neonatal cholestasis,…
  • Biliary Atresia

  • Disorder of porphyrin and heme metabolism

  • Genetic/ Familial Cholestatic Disease

    • Alagille Syndrome

    • Crigler-Najjar syndrome

    • Dubin-Johnson syndrome

    • Progressive familial intrahepatic cholestasis (PFIC)

      Bile is essential in order to break down fats and is produced in the liver. In PFIC patients, the transport of bile from the liver to the intestine is disrupted. Therefore, bile acids and in some cases, other metabolites such…
    • Rotor syndrome

  • Wilson's Disease

    Wilson’s disease is a rare inherited disorder that causes copper to accumulate in your liver, brain and other vital organs. Most people with Wilson’s disease are diagnosed between the ages of 5 and 35, but it can affect younger and…

Structural Liver Disease

  • Biliary Malformations

  • Polycystic Liver Disease (PLD)/ Congenital Fibrosis

    Polycystic Liver Disease (PLD) is a genetic disease, which means it is caused by mutations in your DNA. Patients with PLD have numerous cysts in their liver; a cyst is a closed sac filled with fluid. The buildup of multiple…
  • Rare liver tumors

    • Fibrolamellar hepatocarcinoma

    • Hepatic epitheloid hemangioendothelioma & Angiosarcoma

    • Hepatobiliary tumors with stem cell features & mixed types (CCA/HCC)

    • Hepatoblastoma

    • Intrahepatic Cholangiocarcinoma

    • Primary hepatic neuroendocrine tumors (NET)

  • Vascular Liver Disease

    • Budd-Chiari-Syndrome

    • Early-onset familial non-cirrhotic portal hypertension

    • Nodular regenerative hyperplasia of the liver

Liver disease in pregnancy

  • Acute fatty liver of pregnancy

    Pregnancy related liver disease represents a challenging problem. Often, there is overlap between many of the individual conditions. In general, if any of the following conditions have occurred in one pregnancy, there is a high likelihood of occurrence in a…
  • HELLP syndrome

    Pregnancy related liver disease represents a challenging problem. Often, there is overlap between many of the individual conditions. In general, if any of the following conditions have occurred in one pregnancy, there is a high likelihood of occurrence in a…