Scientific News

The *Call for proposals of a program on orphan medical devices, in particular targeting paediatric patients* by EU4Health is currently [read more]

Biliary Atresia (BA) is a rare paediatric liver disease with an estimated prevalence of 1 / 14.000-21.000 births in Europe (~ 270 cases / year). Its aetiology is still unknown but recent studies favour an aetiology through microbe- or toxin-triggered immune dysregulation in liver and bile ducts leading to obliteration and fibrosis. [read more]

Substantial advances in the diagnosis, treatment, and long-term care of children presenting paediatric liver disease mean that survival into adulthood is now the expectation rather than the exception.  [read more]

Alveolar Echinococcosis (AE) is a rare parasitic disease caused by the infection with the larval stage of the Echinococcus multilocularis tapeworm, known to be endemic in the northern hemisphere, mainly in central Europe and western China.  [read more]

Biliary Atresia (BA) is a rare liver disease of infancy with unclear etiology potentially leading to biliary cirrhosis and liver failure in early life. BA is still one of the main indications for paediatric liver transplantation. To meet this need, the prospective ERN RARE LIVER Biliary Atresia Registry (EBAR) was implemented in the up-and-running R-LIVER registry. [read more]

Non-cirrhotic portal vein thrombosis is associated with one or several underlying risk factors of thrombosis in 60-70 percent of cases, including major prothrombotic risk factor (e.g. myeloproliferative neoplasms, antiphospholipid syndrome, or homozygous factor V Leiden), and transient (local causes) or mild to moderate risk factors (e.g. heterozygous G20210A factor II or G1691A factor V mutations,…).  [read more]