Scientific News

Alveolar Echinococcosis (AE) is a rare parasitic disease caused by the infection with the larval stage of the Echinococcus multilocularis tapeworm, known to be endemic in the northern hemisphere, mainly in central Europe and western China.  [read more]

Biliary Atresia (BA) is a rare liver disease of infancy with unclear etiology potentially leading to biliary cirrhosis and liver failure in early life. BA is still one of the main indications for paediatric liver transplantation. To meet this need, the prospective ERN RARE LIVER Biliary Atresia Registry (EBAR) was implemented in the up-and-running R-LIVER registry. [read more]

The safety of immuno-oncological therapies for patients with autoimmune liver disease has not been adequately studied. To demonstrate the safety of these revolutionary therapies for our patients, we are conducting a retrospective multi-center study. We would invite you to contribute cases of patients with autoimmune liver disease (AILD) who received checkpoint inhibitor therapies.  [read more]

Non-cirrhotic portal vein thrombosis is associated with one or several underlying risk factors of thrombosis in 60-70 percent of cases, including major prothrombotic risk factor (e.g. myeloproliferative neoplasms, antiphospholipid syndrome, or homozygous factor V Leiden), and transient (local causes) or mild to moderate risk factors (e.g. heterozygous G20210A factor II or G1691A factor V mutations,…).  [read more]

While alpha1-antitrypsin deficiency (AATD) - associated liver disease is still greatly understudied, several recently published studies improved our knowledge about this genetic condition caused by mutations in the SERPINA1 gene encoding for alpha-1 antitrypsin. [read more]

The results of the EU survey on the availability of age-appropriate medication for children with autoimmune liver disease (AILD) were recently published with the Journal of Hepatology. [read more]