Scientific News

This letter was published in the Journal of Pediatric Gastroenterology and Nutrition.  [read more]

Background: More patient data are needed to improve research on rare liver diseases. Mobile health apps enable an exhaustive data collection. Therefore, the European Reference Network on Hepatological diseases (ERN RARE-LIVER) intends to implement an app for patients with rare liver diseases communicating with a patient registry, but little is known about which features patients and their healthcare providers regard as being useful. [read more]

Detection of autoantibodies is crucial for the diagnosis autoimmune hepatitis (AIH). Lack of sensitivity and specificity of conventional autoantibodies complicates the diagnostic process. Lack of sensitivity and specificity of conventional autoantibodies complicates the diagnostic process for AIH. Dres. Taubert, Engel and Jaeckel, in collaboration with several colleagues from ERN rare liver and the international autoimmune hepatitis group, aimed to identify more accurate biomarkers for the diagnosis of AIH.  [read more]

During the ongoing SARS-CoV-2 pandemic it is of great importance to identify patients at risk of a severe course of COVID-19. [read more]

Gallstones are a known adverse effect of somatostatin analogs, but it was unclear when they arise on treatment and whether they lead to complications. [read more]

Severe alpha1-antitrypsin (AAT) deficiency (PiZZ genotype) causes liver disease due to accumulation of the mutant Z protein (Z-AAT), which presents histologically as Z-AAT globules. [read more]