Affiliated publications

Acknowledging ERN Rare-liver in a publication adds to the prominence of the network and provides

Scientific Publications

2019

  • Effects of Age and Sex of on Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis. Cheung AC, Lammers WJ, Murillo Perez CF, van Buuren HR, Gulamhusein A, Trivedi PJ, Lazaridis KN, Ponsioen CY, Floreani A, Hirschfield GM, Corpechot C, Mayo MJ, Invernizzi P, Battezzati PM, Parés A, Nevens F, Thorburn D, Mason AL, Carbone M, Kowdley KV, Bruns T, Dalekos GN, Gatselis NK, Verhelst X, Lindor KD, Lleo A, Poupon R, Janssen HL, Hansen BE; Global PBC Study Group. Clin Gastroenterol Hepatol. 2019 Jan 4. pii: S1542-3565(19)30001-1. doi: 10.1016/j.cgh.2018.12.028. [Epub ahead of print]
  • Better end points needed in primary sclerosing cholangitis trials. Gerussi A, Invernizzi P. Nat Rev Gastroenterol Hepatol. 2019 Jan 17. doi: 10.1038/s41575-019-0110-5. [Epub ahead of print] No abstract available.
  • Montano-Loza AJ, Hansen BE, Corpechot C, Roccarina D, Thorburn D, Trivedi P, Hirschfield G, McDowell P, Poupon R, Dumortier J, Bosch A, Giostria E, Conti F, Parés A, Reig A, Floreani A, Russo FP, Goet JC, Harms MH, van Buuren H, Van den Ende N, Nevens F, Verhelst X, Donato MF, Malinverno F, Ebadi M, Mason AL; Global PBC Study Group. Factors Associated With Recurrence of Primary Biliary Cholangitis After Liver Transplantation and Effects on Graft and Patient Survival. Gastroenterology. 2019 Jan;156(1):96-107.e1. doi:10.1053/j.gastro.2018.10.001. Epub 2018 Oct 6. PubMed PMID: 30296431.
  • Congenital Portosystemic Shunts: Current Diagnosis and Management. McLin VA, Franchi-Abella S, Debray D, Guérin F, Beghetti M, Savale L, Wildhaber BE, Gonzales E; Members of the International Registry of Congenital Porto-Systemic Shunts. J Pediatr Gastroenterol Nutr. 2019 Jan 4. doi: 10.1097/MPG.0000000000002263. [Epub ahead of print]

2018

  • Krawczyk M, Koźma M, Szymańska A, Leszko K, Przedniczek M, Mucha K, Foroncewicz B, Pączek L, Moszczuk B, Milkiewicz P, Raszeja-Wyszomirska J. Effects of liver transplantation on health-related quality of life in patients with primary biliary cholangitis. Clin Transplant. 2018 Dec;32(12):e13434. doi: 10.1111/ctr.13434. Epub 2018 Dec 6. PubMed PMID: 30362634.
  • Wunsch E, Raszeja-Wyszomirska J, Barbier O, Milkiewicz M, Krawczyk M, Milkiewicz P. Effect of S-adenosyl-L-methionine on liver biochemistry and quality of life in patients with primary biliary cholangitis treated with ursodeoxycholic acid. A prospective, open label pilot study. J Gastrointestin Liver Dis. 2018 Sep;27(3):273-279. doi: 10.15403/jgld.2014.1121.273.icz. PubMed PMID: 30240471.
  • Janik MK, Wunsch E, Raszeja-Wyszomirska J, Moskwa M, Kruk B, Krawczyk M, Milkiewicz P. Autoimmune hepatitis exerts a profound, negative effect on health-related quality of life: A prospective, single-centre study. Liver Int. 2019 Jan;39(1):215-221. doi: 10.1111/liv.13960. Epub 2018 Sep 29. PubMed PMID: 30204306.
  • Kruk B, Liebe R, Milkiewicz M, Wunsch E, Raszeja-Wyszomirska J, Lammert F, Milkiewicz P, Krawczyk M. PNPLA3 p.I148M and TM6SF2 p.E167K variants do not predispose to liver injury in cholestatic liver diseases: A prospective analysis of 178 patients with PSC. PLoS One. 2018 Aug 30;13(8):e0202942. doi: 10.1371/journal.pone.0202942. eCollection 2018. PubMed PMID: 30161167; PubMed Central PMCID: PMC6117000.
  • Strnad P, Buch S, Hamesch K, Fischer J, Rosendahl J, Schmelz R, Brueckner S, Brosch M, Heimes CV, Woditsch V, Scholten D, Nischalke HD, Janciauskiene S, Mandorfer M, Trauner M, Way MJ, McQuillin A, Reichert MC, Krawczyk M, Casper M, Lammert F, Braun F, von Schönfels W, Hinz S, Burmeister G, Hellerbrand C, Teufel A, Feldman A, Schattenberg JM, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Ridinger M, Wodarz N, Soyka M, Rietschel M, Kiefer F, Weber T, Marhenke S, Vogel A, Hinrichsen H, Canbay A, Schlattjan M, Sosnowsky K, Sarrazin C, von Felden J, Geier A, Deltenre P, Sipos B, Schafmayer C, Nothnagel M, Aigner E, Datz C, Stickel F, Morgan MY, Hampe J, Berg T, Trautwein C. Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis. Gut. 2018 Aug 1. pii: gutjnl-2018-316228. doi: 10.1136/gutjnl-2018-316228.
  • van Aerts RMM, Kievit W, de Jong ME, Ahn C, Bañales JM, Reiterová J, Nevens F, Drenth JPH. Severity in polycystic liver disease is associated with aetiology and female gender: Results of the International PLD Registry. Liver Int. 2018 Sep 17.
  • Nevens F. PBC-transplantation and disease recurrence. Best Pract Res Clin Gastroenterol. 2018 Jun - Aug;34-35:107-111. doi: 10.1016/j.bpg.2018.09.001. Epub 2018 Sep 11. Review
  • Sturm E, Verkade HJ. Disorders of the intrahepatic bile ducts. In: Walker WA, Hamilton JR, Watkins JB, Durie PR, Walker-Smith JA, eds. Pediatric Gastrointestinal Disease. BC Decker, Hamilton; 2018, 6th edition.
  • Al-Dury S, Wahlström A, Wahlin S, Langedijk J, Elferink RO, Ståhlman M, Marschall HU. Pilot study with IBAT inhibitor A4250 for the treatment of cholestatic pruritus in primary biliary cholangitis. Sci Rep. 2018 Apr27;8(1):6658. doi: 10.1038/s41598-018-25214-0. PubMed PMID: 29704003; PubMed Central PMCID: PMC5923243.
  • Marschall HU. Ensuring timely treatment of patients with primary biliary cholangitis. Lancet Gastroenterol Hepatol. 2018 Sep;3(9):591-593. doi:10.1016/S2468-1253(18)30177-8. Epub 2018 Jul 13. PubMed PMID: 30017647.
  • Jung F, Cazzagon N, Vettorazzi E, Corpechot C, Chazouilleres O, Arrivé L, Lohse AW, Schramm C, Ehlken H. Rate of Spleen Length Progression is a Marker of Outcome in Patients with Primary Sclerosing Cholangitis. Clin Gastroenterol Hepatol. 2019 Jan 4. pii: S1542-3565(19)30006-0. doi: 10.1016/j.cgh.2018.12.033. [Epub ahead of print] PubMed PMID: 30616025.
  • Corpechot C, Chazouillères O, Rousseau A, Le Gruyer A, Habersetzer F, Mathurin P, Goria O, Potier P, Minello A, Silvain C, Abergel A, Debette-Gratien M, Larrey D, Roux O, Bronowicki JP, Boursier J, de Ledinghen V, Heurgue-Berlot A, Nguyen-Khac E, Zoulim F, Ollivier-Hourmand I, Zarski JP, Nkontchou G, Lemoinne S, Humbert L, Rainteau D, Lefèvre G, de Chaisemartin L, Chollet-Martin S, Gaouar F, Admane FH, Simon T, Poupon R. A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis. N Engl J Med. 2018 Jun 7;378(23):2171-2181. doi: 10.1056/NEJMoa1714519. PubMed PMID: 29874528.
  • Female preponderance of primary biliary cholangitis is all about our understanding of its autoimmune nature. Carbone M, Bonato G, Invernizzi P. Hepatology. 2018 Apr;67(4):1210-1212. doi: 10.1002/hep.29625. Epub 2018 Feb 19. No abstract available
  • Geoepidemiology of Primary Biliary Cholangitis: Lessons from Switzerland. Terziroli Beretta-Piccoli B, Stirnimann G, Cerny A, Semela D, Hessler R, Helbling B, Stickel F, Kalid-de Bakker C, Bihl F, Giostra E, Filipowicz Sinnreich M, Oneta C, Baserga A, Invernizzi P, Carbone M, Mertens J. Clin Rev Allergy Immunol. 2018 Apr;54(2):295-306. doi: 10.1007/s12016-017-8656-x
  • Milder disease stage in patients with primary biliary cholangitis over a 44-year period: A changing natural history. Murillo Perez CF, Goet JC, Lammers WJ, Gulamhusein A, van Buuren HR, Ponsioen CY, Carbone M, Mason A, Corpechot C, Invernizzi P, Mayo MJ, Battezzati PM, Floreani A, Pares A, Nevens F, Kowdley KV, Bruns T, Dalekos GN, Thorburn D, Hirschfield G, LaRusso NF, Lindor KD, Zachou K, Poupon R, Trivedi PJ, Verhelst X, Janssen HLA, Hansen BE; GLOBAL PBC Study Group. Hepatology. 2018 May;67(5):1920-1930. doi: 10.1002/hep.29717. Epub 2018 Apr 6
  • Clinical and prognostic implications of acute onset of Autoimmune Hepatitis: An Italian multicentre study. Muratori P, Carbone M, Stangos G, Perini L, Lalanne C, Ronca V, Cazzagon N, Bianchi G, Lenzi M, Floreani A, Invernizzi P, Muratori L. Dig Liver Dis. 2018 Jul;50(7):698-702. doi: 10.1016/j.dld.2018.02.015. Epub 2018 Mar 2
  • Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2-/- mice and human cholangiocarcinoma tumorigenesis. Kennedy L, Hargrove L, Demieville J, Karstens W, Jones H, DeMorrow S, Meng F, Invernizzi P, Bernuzzi F, Alpini G, Smith S, Akers A, Meadows V, Francis H. Hepatology. 2018 Mar 30. doi: 10.1002/hep.29898. [Epub ahead of print]
  • NI-0801, an anti-chemokine (C-X-C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid. de Graaf KL, Lapeyre G, Guilhot F, Ferlin W, Curbishley SM, Carbone M, Richardson P, Moreea S, McCune CA, Ryder SD, Chapman RW, Floreani A, Jones DE, de Min C, Adams DH, Invernizzi P. Hepatol Commun. 2018 Mar 23;2(5):492-503. doi: 10.1002/hep4.1170. eCollection 2018 May
  • Clinical application of the GLOBE and United Kingdom-primary biliary cholangitis risk scores in a trial cohort of patients with primary biliary cholangitis. Carbone M, Harms MH, Lammers WJ, Marmon T, Pencek R, MacConell L, Shapiro D, Jones DE, Mells GF, Hansen BE. Hepatol Commun. 2018 Apr 19;2(6):683-692. doi: 10.1002/hep4.1180. eCollection 2018 Jun
  • Risk stratification and prognostic modelling in primary biliary cholangitis. Goet JC, Harms MH, Carbone M, Hansen BE. Best Pract Res Clin Gastroenterol. 2018 Jun - Aug;34-35:95-106. doi: 10.1016/j.bpg.2018.06.006. Epub 2018 Jun 18. Review
  • Support of precision medicine through risk-stratification in autoimmune liver diseases - histology, scoring systems, and non-invasive markers. Bossen L, Gerussi A, Lygoura V, Mells GF, Carbone M, Invernizzi P Autoimmun Rev. 2018 Sep;17(9):854-865. doi: 10.1016/j.autrev.2018.02.013. Epub 2018 Jul 11. Review
  • Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score. Carbone M, Nardi A, Flack S, Carpino G, Varvaropoulou N, Gavrila C, Spicer A, Badrock J, Bernuzzi F, Cardinale V, Ainsworth HF, Heneghan MA, Thorburn D, Bathgate A, Jones R, Neuberger JM, Battezzati PM, Zuin M, Taylor-Robinson S, Donato MF, Kirby J, Mitchell-Thain R, Floreani A, Sampaziotis F, Muratori L, Alvaro D, Marzioni M, Miele L, Marra F, Giannini E, Gaudio E, Ronca V, Bonato G, Cristoferi L, Malinverno F, Gerussi A, Stocken DD, Cordell HJ, Hirschfield GM, Alexander GJ, Sandford RN, Jones DE, Invernizzi P, Mells GF; Italian PBC Study Group and the UK–PBC Consortium. Lancet Gastroenterol Hepatol. 2018 Sep;3(9):626-634. doi: 10.1016/S2468-1253(18)30163-8. Epub 2018 Jul 13
  • "I Miss My Liver." Nonmedical Sources in the History of Hepatocentrism. Orlandi R, Cianci N, Invernizzi P, Cesana G, Riva MA. Hepatol Commun. 2018 Aug 6;2(8):982-989. doi: 10.1002/hep4.1224. eCollection 2018 Aug
  • Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2-/- mice and human primary sclerosing cholangitis. Meng F, Kennedy L, Hargrove L, Demieville J, Jones H, Madeka T, Karstens A, Chappell K, Alpini G, Sybenga A, Invernizzi P, Bernuzzi F, DeMorrow S, Francis H. Lab Invest. 2018 Nov;98(11):1465-1477. doi: 10.1038/s41374-018-0101-0. Epub 2018 Aug 24
  • Individualizing Care: Management Beyond Medical Therapy. Cristoferi L, Nardi A, Invernizzi P, Mells G, Carbone M. Clin Liver Dis. 2018 Aug;22(3):545-561. doi: 10.1016/j.cld.2018.03.006. Review.
  • Geoepidemiology and (epi-)genetics in primary biliary cholangitis. Rosa R, Cristoferi L, Tanaka A, Invernizzi P. Best Pract Res Clin Gastroenterol. 2018 Jun - Aug;34-35:11-15. doi: 10.1016/j.bpg.2018.05.011. Epub 2018 May 16. Review.
  • Prognostic models in primary biliary cholangitis. Cristoferi L, Nardi A, Ronca V, Invernizzi P, Mells G, Carbone M. J Autoimmun. 2018 Dec;95:171-178. doi: 10.1016/j.jaut.2018.10.024. Epub 2018 Nov 9. Review.
  • The immunobiology of female predominance in primary biliary cholangitis. Gerussi A, Cristoferi L, Carbone M, Asselta R, Invernizzi P. J Autoimmun. 2018 Dec;95:124-132. doi: 10.1016/j.jaut.2018.10.015. Epub 2018 Oct 25. Review.
  • Kowdley KV, Luketic V, Chapman R, Hirschfield GM, Poupon R, Schramm C, Vincent C, Rust C, Parés A, Mason A, Marschall HU, Shapiro D, Adorini L, Sciacca C, Beecher-Jones T, Böhm O, Pencek R, Jones D; Obeticholic Acid PBC Monotherapy Study Group. A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis. Hepatology. 2018 May;67(5):1890-1902. doi: 10.1002/hep.29569. Epub 2018 Jan 29. PubMed PMID: 29023915; PubMed Central PMCID: PMC5947631.
  • Lemoinne S, Pares A, Reig A, Ben Belkacem K, Kemgang Fankem AD, Gaouar F, Poupon R, Housset C, Corpechot C, Chazouillères O. Primary sclerosing cholangitis response to the combination of fibrates with ursodeoxycholic acid: French-Spanish experience. Clin Res Hepatol Gastroenterol. 2018 Dec;42(6):521-528. doi: 10.1016/j.clinre.2018.06.009. Epub 2018 Aug 9. PubMed PMID: 30100231.
  • European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu; European Association for the Study of the Liver. EASL Clinical Practice Guidelines on nutrition in chronic liver disease. J Hepatol. 2019 Jan;70(1):172-193. doi: 10.1016/j.jhep.2018.06.024. Epub 2018 Aug 23. PubMed PMID: 30144956.
  • Harris T, Sandford R, de Coninck B, Devuyst O, Drenth JPH, Ecder T, Kent A, Gansevoort RT, Górriz JL, Ong ACM, Pirson Y, Torres VE, Budde K, Clément D, Derchi LE, Eleftheroudi M, Levtchenko E, Peters D, Van Poppel H, Vanholder R. European ADPKD Forum multidisciplinary position statement on autosomal dominant polycystic kidney disease care. NEPHROLOGY DIALYSIS TRANSPLANTATION Volume: 33 Issue: 4 Pages: 563-573 Published: APR 2018By:
  • Wijnands, T. F. M., T. J. G. Gevers, M. A. Lantinga, R. H. Te Morsche, L. J. Schultze Kool and J. P. H. Drenth (2018). "Pasireotide does not improve efficacy of aspiration sclerotherapy in patients with large hepatic cysts, a randomized controlled trial." Eur Radiol 28(6): 2682-2689.
  • Wijnands, T. F., B. Schoenemeier, A. Potthoff, T. J. Gevers, H. Groenewoud, M. J. Gebel, K. Rifai, M. P. Manns and J. P. Drenth (2018). "Ethanol sclerotherapy or polidocanol sclerotherapy for symptomatic hepatic cysts." United European Gastroenterol J 6(6): 919-925.
  • van de Laarschot, L. F. M. and J. P. H. Drenth (2018). "Genetics and mechanisms of hepatic cystogenesis." Biochim Biophys Acta 1864(4 Pt B): 1491-1497.
  • van Aerts, R. M. M., M. Kolkman, W. Kievit, T. J. G. Gevers, F. Nevens and J. P. H. Drenth (2018). "Drug holiday in patients with polycystic liver disease treated with somatostatin analogues." Therap Adv Gastroenterol 11: 1756284818804784.
  • Neijenhuis, M. K., W. Kievit, S. M. Verheesen, H. M. D'Agnolo, T. J. Gevers and J. P. Drenth (2018). "Impact of liver volume on polycystic liver disease-related symptoms and quality of life." United European Gastroenterol J 6(1): 81-88.
  • Neijenhuis, M., T. J. G. Gevers, T. D. Atwell, T. J. Gunneson, A. C. Schimek, W. Kievit, J. P. H. Drenth and P. S. Kamath (2018). "Development and Validation of a Patient-Reported Outcome Measurement for Symptom Assessment in Cirrhotic Ascites." Am J Gastroenterol 113(4): 567-575.
  • Meijer, E., F. W. Visser, R. M. M. van Aerts, C. J. Blijdorp, N. F. Casteleijn, H. M. A. D'Agnolo, S. E. I. Dekker, J. P. H. Drenth, J. W. de Fijter, M. D. A. van Gastel, T. J. Gevers, M. A. Lantinga, M. Losekoot, A. L. Messchendorp, M. K. Neijenhuis, M. J. Pena, D. J. M. Peters, M. Salih, D. Soonawala, E. M. Spithoven, J. F. Wetzels, R. Zietse and R. T. Gansevoort (2018). "Effect of Lanreotide on Kidney Function in Patients With Autosomal Dominant Polycystic Kidney Disease: The DIPAK 1 Randomized Clinical Trial." Jama 320(19): 2010-2019.
  • Fine-tuning of SIRT1 expression is essential to protect the liver from cholestatic liver disease. Blokker BA, Maijo M, Echeandia M, Galduroz M, Patterson AM, Ten A, Philo M, Schungel R, Gutierrez-de Juan V, Halilbasic E, Fuchs C, Le Gall G, Milkiewicz M, Milkiewicz P, Banales JM, Rushbrook SM, Mato JM, Trauner M, Müller M, Martínez-Chantar ML, Varela-Rey M, Beraza N. Hepatology. 2018 Sep 19. doi: 10.1002/hep.30275. [Epub ahead of print]
  • Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis. Banales JM, Iñarrairaegui M, Arbelaiz A, Milkiewicz P, Muntane J, Muñoz-Bellvis L, La Casta A, Gonzalez LM, Arretxe E, Alonso C, Martínez-Arranz I, Lapitz A, Santos-Laso A, Avila MA, Martínez-Chantar ML, Bujanda L, Marin JJG, Sangro B, Macias RIR. Hepatology. 2018 Oct 16. doi: 10.1002/hep.30319. [Epub ahead of print]
  • The epidermal growth factor receptor ligand amphiregulin protects from cholestatic liver injury and regulates bile acids synthesis. Santamaría E, Rodríguez-Ortigosa CM, Uriarte I, Latasa MU, Urtasun R, Alvarez-Sola G, Bárcena-Varela M, Colyn L, Arcelus S, Jiménez M, Deutschmann K, Peleteiro-Vigil A, Gómez-Cambronero J, Milkiewicz M, Milkiewicz P, Sangro B, Keitel V, Monte MJ, Marin JJ, Fernández-Barrena MG, Ávila MA, Berasain C.Hepatology. 2018 Nov 8. doi: 10.1002/hep.30348. [Epub ahead of print]
  • Ageing-related expression of Twinfilin-1 regulates cholangiocyte biological response to injury.Maroni L, Pinto C, Giordano DM, Saccomanno S, Banales JM, Spallacci D, Albertini MC, Orlando F, Provinciali M, Milkiewicz M, Melum E, Ciriza IL, Milkiewicz P, Rychlicki C, Trozzi L, Scarpelli M, Benedetti A, Svegliati Baroni G, Marzioni M. Hepatology. 2018 Dec 18. doi: 10.1002/hep.30466. [Epub ahead of print]
  • Bile Acids, the Microbiome, Immunity, and Liver Tumors Schramm, C. 30.08.2018 in : NEW ENGL J MED. 379, 9, S. 888-890
  • Recommendations on the use of magnetic resonance imaging for collaborative multicenter studies in PSC Ringe, K. I., Grigoriadis, A., Halibasic, E., Wacker, F., Manns, M. P., Schramm, C., Lenzen, H. & MRI working group of the IPSCSG 17.09.2018 in : HEPATOLOGY.
  • Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis Alberts, R. , de Vries, E. M. G. , Goode, E. C. , Jiang, X. , Sampaziotis, F. , Rombouts, K. , Böttcher, K. , Folseraas, T. , Weismüller, T. J. , Mason, A. L. , Wang, W. , Alexander, G. , Alvaro, D. , Bergquist, A. , Björkström, N. K. , Beuers, U. , Björnsson, E. , Boberg, K. M. , Bowlus, C. L. , Bragazzi, M. C. &55 mehr Carbone, M., Chazouillères, O., Cheung, A., Dalekos, G., Eaton, J., Eksteen, B., Ellinghaus, D., Färkkilä, M., Festen, E. A. M., Floreani, A., Franceschet, I., Gotthardt, D. N., Hirschfield, G. M., Hoek, B. V., Holm, K., Hohenester, S., Hov, J. R., Imhann, F., Invernizzi, P., Juran, B. D., Lenzen, H., Lieb, W., Liu, J. Z., Marschall, H-U., Marzioni, M., Melum, E., Milkiewicz, P., Müller, T., Pares, A., Rupp, C., Rust, C., Sandford, R. N., Schramm, C., Schreiber, S., Schrumpf, E., Silverberg, M. S., Srivastava, B., Sterneck, M., Teufel, A., Vallier, L., Verheij, J., Vila, A. V., Vries, B. D., Zachou, K., Chapman, R. W., Manns, M. P., Pinzani, M., Rushbrook, S. M., Lazaridis, K. N., Franke, A., Anderson, C. A., Karlsen, T. H., Ponsioen, C. Y., Weersma, R. K. & International PSC Study Group, The UK PSC Consortium 08.2018 in : GUT. 67, 8, S. 1517-1524
  • Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom Dyson, J. K., Wong, L. L., Bigirumurame, T., Hirschfield, G. M., Kendrick, S., Oo, Y. H., Lohse, A. W., Heneghan, M. A., Jones, D. E. J. & UK-AIH Consortium 11.2018 in : ALIMENT PHARM THER. 48, 9, S. 951-960
  • Primary sclerosing cholangitis. Dyson, J. K., Beuers, U., Jones, D. E. J., Lohse, A. W. & Hudson, M. 23.06.2018 in : LANCET. 391, 10139, S. 2547-2559
  • Autoimmune hepatitis From current knowledge and clinical practice to future research agenda. Sebode, M., Hartl, J., Vergani, D., Lohse, A. W. & International Autoimmune Hepatitis Group (IAIHG) 01.2018 in : LIVER INT. 38, 1, S. 15-22
  • Access to care in rare liver diseases: New challenges and new opportunities: Jones, D. E. J., Sturm, E. & Lohse, A. W. 03.2018 in : J HEPATOL. 68, 3, S. 577-585
  • Transient portal vein thrombosis in liver cirrhosis. Qi X, Guo X, Yoshida EM, Méndez-Sánchez N, De Stefano V, Tacke F, Mancuso A, Sugawara Y, Yang SS, Teschke R, Arora A, Valla DC. BMC Med. 2018 Jun 5;16(1):83. doi: 10.1186/s12916-018-1069-8. Review. PMID: 29871683
  • Pregnancy in idiopathic non-cirrhotic portal hypertension: A multicentric study on maternal and fetal management and outcome. Andrade F, Shukla A, Bureau C, Senzolo M, D'Alteroche L, Heurgué A, Garcia-Pagan JC, Turon F, Oberti F, Tripathi D, Roux O, Ceccaldi PF, de Raucourt E, Payancé A, Valla D, Plessier A, Rautou PE; VALDIG investigators. J Hepatol. 2018 Dec;69(6):1242-1249. doi: 10.1016/j.jhep.2018.08.007. Epub 2018 Aug 21.
  • Mutations in the novel gene FOPV are associated with familial autosomal dominant and non-familial obliterative portal venopathy. Besmond C, Valla D, Hubert L, Poirier K, Grosse B, Guettier C, Bernard O, Gonzales E, Jacquemin E. Liver Int. 2018 Feb;38(2):358-364. doi: 10.1111/liv.13547. Epub 2017 Sep 12.
  • Zimmer V, Bohle RM, Weber SN, Lammert F, Jüngst C. Benign recurrent intrahepatic cholestasis (BRIC)-like episode associated with ATP8B1 variation underlying protracted cholestatic course of acute hepatitis E virus infection. Dig Liver Dis. 2018 Feb;50(2):206-207. doi: 10.1016/j.dld.2017.10.022. Epub 2017 Nov 8. PubMed PMID: 29191380.
  • Reichert MC, Lammert F. ABCB4 Gene Aberrations in Human Liver Disease: An Evolving Spectrum. Semin Liver Dis. 2018 Nov;38(4):299-307. doi: 10.1055/s-0038-1667299. Epub 2018 Oct 24. Review. PubMed PMID: 30357767.
  • Holz R, Kremer AE, Lütjohann D, Wasmuth HE, Lammert F, Krawczyk M. Can genetic testing guide the therapy of cholestatic pruritus? A case of benign recurrent intrahepatic cholestasis type 2 with severe nasobiliary drainage-refractory itch. Hepatol Commun. 2018 Jan 10;2(2):152-154. doi: 10.1002/hep4.1144. eCollection 2018 Feb. PubMed PMID: 29404523; PubMed Central PMCID: PMC5796322.
  • Krupa Ł, Staroń R, Pająk J, Lammert F, Krawczyk M, Gutkowski K. Secondary systemic amyloidosis diagnosed by endoscopic ultrasound-guided liver biopsy. J Gastrointestin Liver Dis. 2018 Mar;27(1):101-102. doi:10.15403/jgld.2014.1121.271.kru. PubMed PMID: 29557423.

2017

  • Temmerman F, Chen F, Libbrecht L, Vander Elst I, Windmolders P, Feng Y, Ni Y, De Smedt H, Nevens F, van Pelt J. Everolimus halts hepatic cystogenesis in a rodent model of polycystic-liver-disease. World J Gastroenterol. 2017 Aug 14;23(30):5499-5507. doi: 10.3748/wjg.v23.i30.5499
  • EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. - Journal Of hepatology 2017 vol 67: 145-172. http://www.easl.eu/medias/cpg/Primary%20biliary%20cholangitis/English-report.pdf
  • Hartleif S, Schumm M, Döring M, Mezger M, Lang P, Dahlke MH, Riethmüller J, Königsrainer A, Handgretinger R, Nadalin S, Sturm E. Safety and Tolerance of Donor-Derived Mesenchymal Stem Cells in Pediatric Living-Donor Liver Transplantation: The MYSTEP1 Study. Stem Cells Int. 2017;2017:2352954.
  • Felux J, Sturm E, Busch A, Zerabruck E, Graepler F, Stüker D, Manger A, Kirschner HJ, Blumenstock G, Malek NP, Goetz M. ERCP in infants, children and adolescents is feasible and safe: results from a tertiary care center. United European Gastroenterol J. 2017 Nov;5(7):1024-1029.
  • Danielsson Borssén Å, Marschall HU, Bergquist A, Rorsman F, Weiland O, Kechagias S, Nyhlin N, Verbaan H, Nilsson E, Werner M. Epidemiology and causes of death in a Swedish cohort of patients with autoimmune hepatitis. Scand J Gastroenterol. 2017 Sep;52(9):1022-1028. doi: 10.1080/00365521.2017.1335772. Epub 2017 May 31. PubMed PMID: 28562110.
  • Molinaro A, Marschall HU. Why Doesn't Primary Biliary Cholangitis Respond to Immunosuppressive Medications? Curr Hepatol Rep. 2017;16(2):119-123. doi: 10.1007/s11901-017-0345-y. Epub 2017 Apr 27. Review. PubMed PMID: 28706773; PubMed Central PMCID: PMC5486599.
  • Borssén ÅD, Palmqvist R, Kechagias S, Marschall HU, Bergquist A, Rorsman F, Weiland O, Verbaan H, Nyhlin N, Nilsson E, Werner M. Histological improvement of liver fibrosis in well-treated patients with autoimmune hepatitis: A cohortstudy. Medicine (Baltimore). 2017 Aug;96(34):e7708. doi: 10.1097/MD.0000000000007708. PubMed PMID: 28834875; PubMed Central PMCID: PMC5571997.
  • 87. The fingerprint of antimitochondrial antibodies and the etiology of primary biliary cholangitis. Shuai Z, Wang J, Badamagunta M, Choi J, Yang G, Zhang W, Kenny TP, Guggenheim K, Kurth MJ, Ansari AA, Voss J, Coppel RL, Invernizzi P, Leung PSC, Gershwin ME. Hepatology. 2017 May;65(5):1670-1682. doi: 10.1002/hep.29059. Epub 2017 Mar 3
  • Primary Biliary Cholangitis Associated with Skin Disorders: A Case Report and Review of the Literature. Terziroli Beretta-Piccoli B, Guillod C, Marsteller I, Blum R, Mazzucchelli L, Mondino C, Invernizzi P, Gershwin ME, Mainetti C. Arch Immunol Ther Exp (Warsz). 2017 Aug;65(4):299-309. doi: 10.1007/s00005-016-0448-0. Epub 2017 Jan 25. Review
  • Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells. Wan Y, Meng F, Wu N, Zhou T, Venter J, Francis H, Kennedy L, Glaser T, Bernuzzi F, Invernizzi P, Glaser S, Huang Q, Alpini G. Hepatology. 2017 Aug;66(2):528-541. doi: 10.1002/hep.29138. Epub 2017 Jun 19
  • Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b. Kyritsi K, Meng F, Zhou T, Wu N, Venter J, Francis H, Kennedy L, Onori P, Franchitto A, Bernuzzi F, Invernizzi P, McDaniel K, Mancinelli R, Alvaro D, Gaudio E, Alpini G, Glaser S. Am J Pathol. 2017 Jul;187(7):1551-1565. doi: 10.1016/j.ajpath.2017.03.013. Epub 2017 May 12
  • Primary Biliary Cholangitis: advances in management and treatment of the disease. Invernizzi P, Floreani A, Carbone M, Marzioni M, Craxi A, Muratori L, Vespasiani Gentilucci U, Gardini I, Gasbarrini A, Kruger P, Mennini FS, Ronco V, Lanati E, Canonico PL, Alvaro D. Dig Liver Dis. 2017 Aug;49(8):841-846. doi: 10.1016/j.dld.2017.05.001. Epub 2017 May 8
  • Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2-/- mice. Hall C, Ehrlich L, Meng F, Invernizzi P, Bernuzzi F, Lairmore TC, Alpini G, Glaser S. J Surg Res. 2017 Sep;217:160-169. doi: 10.1016/j.jss.2017.05.020. Epub 2017 May 11
  • Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR-200b down-regulation. Wu N, Meng F, Zhou T, Han Y, Kennedy L, Venter J, Francis H, DeMorrow S, Onori P, Invernizzi P, Bernuzzi F, Mancinelli R, Gaudio E, Franchitto A, Glaser S, Alpini G. FASEB J. 2017 Oct;31(10):4305-4324. doi: 10.1096/fj.201700097R. Epub 2017 Jun 20
  • A functional characteristic of cysteine-rich protein 61: Modulation of myeloid-derived suppressor cells in liver inflammation. Zhang H, Lian M, Zhang J, Bian Z, Tang R, Miao Q, Peng Y, Fang J, You Z, Invernizzi P, Wang Q, Gershwin ME, Ma X. Hepatology. 2018 Jan;67(1):232-246. doi: 10.1002/hep.29418. Epub 2017 Nov 17
  • Skin Manifestations Associated with Autoimmune Liver Diseases: a Systematic Review. Terziroli Beretta-Piccoli B, Invernizzi P, Gershwin ME, Mainetti C. Clin Rev Allergy Immunol. 2017 Dec;53(3):394-412. doi: 10.1007/s12016-017-8649-9. Review
  • From pathogenesis to novel therapies in the treatment of primary biliary cholangitis. Ronca V, Carbone M, Bernuzzi F, Malinverno F, Mousa HS, Gershwin ME, Invernizzi P. Expert Rev Clin Immunol. 2017 Dec;13(12):1121-1131. doi: 10.1080/1744666X.2017.1391093. Epub 2017 Nov 9. Review.
  • Dysregulation of Iron Metabolism in Cholangiocarcinoma Stem-like Cells. Raggi C, Gammella E, Correnti M, Buratti P, Forti E, Andersen JB, Alpini G, Glaser S, Alvaro D, Invernizzi P, Cairo G, Recalcati S. Sci Rep. 2017 Dec 15;7(1):17667. doi: 10.1038/s41598-017-17804-1
  • Optimising the clinical strategy for autoimmune liver diseases: Principles of value-based medicine. Carbone M, Cristoferi L, Cortesi PA, Rota M, Ciaccio A, Okolicsanyi S, Gemma M, Scalone L, Cesana G, Fabris L, Colledan M, Fagiuoli S, Ideo G, Belli LS, Munari LM, Mantovani L, Strazzabosco M. Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1415-1422. doi: 10.1016/j.bbadis.2017.08.025. Epub 2017 Aug 24
  • Poisson J; Plessier A; Kiladjian JJ; Turon F; Cassinat B; Andreoli A; De Raucourt E; Goria O; Zekrini K; Bureau C; Lorre F; Cervantes F; Colomer D; Durand F; Garcia-Pagan JC; Casadevall N; Valla DC; Rautou PE; Marzac C; French national network for vascular liver diseases. Selective testing for calreticulin gene mutations in patients with splanchnic vein thrombosis: A prospective cohort study. J Hepatol. 2017 Sep;67(3):501-507. doi: 10.1016/j.jhep.2017.04.021.
  • De Gottardi A; Trebicka J; Klinger C; Plessier A; Seijo S; Terziroli B; Magenta L; Semela D; Buscarini E; Langlet P; Görtzen J; Puente A; Müllhaupt B; Navascuès C; Nery F; Deltenre P; Turon F; Engelmann C; Arya R; Caca K; Peck-Radosavljevic M; Leebeek FW; Valla D; Garcia-Pagan JC; VALDIG Investigators. Antithrombotic treatment with direct-acting oral anticoagulants in patients with splanchnic vein thrombosis and cirrhosis. Liver Int. 2017 May;37(5):694-699. doi: 10.1111/liv.13285.
  • de Vries EMG, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M. Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study. Liver Int. 2017 Oct;37(10):1554-1561. doi: 10.1111/liv.13402. Epub 2017 Apr 13. PubMed PMID: 28267887.
  • Bolier R, de Vries ES, Parés A, Helder J, Kemper EM, Zwinderman K, Elferink RPO, Beuers U; Netherlands Association for the Study of the Liver (NASL) Cholestatic Liver Diseases Study Group. Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial. Trials. 2017 May 23;18(1):230. doi: 10.1186/s13063-017-1966-8. PubMed PMID: 28535810; PubMedCentral PMCID: PMC5442649.
  • Efe C, Hagström H, Ytting H, Bhanji RA, Müller NF, Wang Q, Purnak T, Muratori L, Werner M, Marschall HU, Muratori P, Gunşar F, Klintman D, Parés A, Heurgué-Berlot A, Schiano TD, Cengiz M, May-Sien Tana M, Ma X, Montano-Loza AJ, Berg T, Verma S, Larsen FS, Ozaslan E, Heneghan MA, Yoshida EM, Wahlin S. Efficacy and Safety of Mycophenolate Mofetil and Tacrolimus as Second-line Therapy for Patients With Autoimmune Hepatitis. Clin Gastroenterol Hepatol. 2017 Dec;15(12):1950-1956.e1. doi: 10.1016/j.cgh.2017.06.001. Epub 2017 Jun 8. PubMed PMID: 28603052.
  • Harms MH, Lammers WJ, Thorburn D, Corpechot C, Invernizzi P, Janssen HLA, Battezzati PM, Nevens F, Lindor KD, Floreani A, Ponsioen CY, Mayo MJ, Dalekos GN, Bruns T, Parés A, Mason AL, Verhelst X, Kowdley KV, Goet JC, Hirschfield GM, Hansen BE, van Buuren HR. Major Hepatic Complications in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis: Risk Factors and Time Trends in Incidence and Outcome. Am J Gastroenterol. 2018 Feb;113(2):254-264. doi: 10.1038/ajg.2017.440. Epub 2017 Dec 12. PubMed PMID: 29231188.
  • Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. Fawaz R1, Baumann U, Ekong U, Fischler B, Hadzic N, Mack CL, McLin VA, Molleston JP, Neimark E, Ng VL, Karpen SJ. J Pediatr Gastroenterol Nutr. 2017 Jan;64(1):154-168. doi: 10.1097/MPG.0000000000001334.
  • Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma. Arbelaiz A, Azkargorta M, Krawczyk M, Santos-Laso A, Lapitz A, Perugorria MJ, Erice O, Gonzalez E, Jimenez-Agüero R, Lacasta A, Ibarra C, Sanchez-Campos A, Jimeno JP, Lammert F, Milkiewicz P, Marzioni M, Macias RIR, Marin JJG, Patel T, Gores GJ, Martinez I, Elortza F, Falcon-Perez JM, Bujanda L, Banales JM. Hepatology. 2017 Oct;66(4):1125-1143. doi: 10.1002/hep.29291. Epub 2017 Aug 26.
  • Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis Weismüller, T. J. , Trivedi, P. J. , Bergquist, A. , Imam, M. , Lenzen, H. , Ponsioen, C. Y. , Holm, K. , Gotthardt, D. , Färkkilä, M. A. , Marschall, H-U. , Thorburn, D. , Weersma, R. K. , Fevery, J. , Mueller, T. , Chazouillères, O. , Schulze, K. , Lazaridis, K. N. , Almer, S. , Pereira, S. P. , Levy, C. &40 mehr Mason, A. L., Naess, S., Bowlus, C. L., Floreani, A., Halilbasic, E., Yimam, K. K., Milkiewicz, P., Beuers, U., Huynh, D. K., Pares, A., Manser, C. N., Dalekos, G. N., Eksteen, B., Invernizzi, P., Berg, C. P., Kirchner, G. I., Sarrazin, C., Zimmer, V., Fabris, L., Braun, F., Marzioni, M., Juran, B. D., Said, K., Rupp, C., Jokelainen, K., Benito de Valle, M., Saffioti, F., Cheung, A., Trauner, M., Schramm, C., Chapman, R. W., Karlsen, T. H., Schrumpf, E., Strassburg, C-P., Manns, M. P., Lindor, K. D., Hirschfield, G. M., Hansen, B. E., Boberg, K. M. & International PSC Study Group 06.2017 in : GASTROENTEROLOGY. 152, 8, S. 1975-1984.e8
  • Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline. Aabakken, L., Karlsen, T. H., Albert, J., Arvanitakis, M., Chazouilleres, O., Dumonceau, J-M., Färkkilä, M., Fickert, P., Hirschfield, G. M., Laghi, A., Marzioni, M., Fernandez, M., Pereira, S. P., Pohl, J., Poley, J-W., Ponsioen, C. Y., Schramm, C., Swahn, F., Tringali, A. & Hassan, C. 06.2017 in : ENDOSCOPY. 49, 6, S. 588-608
  • norUrsodeoxycholic Acid Improves Cholestasis in Primary Sclerosing Cholangitis Fickert, P. , Hirschfield, G. M. , Denk, G. , Marschall, H-U. , Altorjay, I. , Färkkilä, M. , Schramm, C. , Spengler, U. , Chapman, R. W. , Bergquist, A. , Schrumpf, E. , Nevens, F. , Trivedi, P. J. , Reiter, F. P. , Tornai, I. , Halilbasic, E. , Greinwald, R. , Pröls, M. , Manns, M. P. , Trauner, M. &1 mehr European PSC norUDCA Study Group 09.2017 in : J HEPATOL. 67, 3, S. 549-558
  • Recommendations on the use of MRI in PSC-A position statement from the International PSC study group. Schramm, C., Eaton, J. E., Ringe, K. I., Venkatesh, S., Yamamura, J. & MRI working group of the IPSCSG 11.2017 in : HEPATOLOGY. 66, 5, S. 1675-1688
  • 24. Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. Ji, S-G. , Juran, B. D. , Mucha, S. , Folseraas, T. , Jostins, L. , Melum, E. , Kumasaka, N. , Atkinson, E. J. , Schlicht, E. M. , Liu, J. Z. , Shah, T. , Gutierrez-Achury, J. , Boberg, K. M. , Bergquist, A. , Vermeire, S. , Eksteen, B. , Durie, P. R. , Farkkila, M. , Müller, T. , Schramm, C. &51 mehr Sterneck, M., Weismüller, T. J., Gotthardt, D. N., Ellinghaus, D., Braun, F., Teufel, A., Laudes, M., Lieb, W., Jacobs, G., Beuers, U., Weersma, R. K., Wijmenga, C., Marschall, H-U., Milkiewicz, P., Pares, A., Kontula, K., Chazouillères, O., Invernizzi, P., Goode, E., Spiess, K., Moore, C., Sambrook, J., Ouwehand, W. H., Roberts, D. J., Danesh, J., Floreani, A., Gulamhusein, A. F., Eaton, J. E., Schreiber, S., Coltescu, C., Bowlus, C. L., Luketic, V. A., Odin, J. A., Chopra, K. B., Kowdley, K. V., Chalasani, N., Manns, M. P., Srivastava, B., Mells, G., Sandford, R. N., Alexander, G., Gaffney, D. J., Chapman, R. W., Hirschfield, G. M., de Andrade, M., Rushbrook, S. M., Franke, A., Karlsen, T. H., Lazaridis, K. N., Anderson, C. A. & UK-PSC Consortium 02.2017 in : NAT GENET. 49, 2, S. 269-273
  • Expert clinical management of autoimmune hepatitis in the real world. Liberal, R., de Boer, Y. S., Andrade, R. J., Bouma, G., Dalekos, G. N., Floreani, A., Gleeson, D., Hirschfield, G. M., Invernizzi, P., Lenzi, M., Lohse, A. W., Macedo, G., Milkiewicz, P., Terziroli, B., van Hoek, B., Vierling, J. M., Heneghan, M. A. & International Autoimmune Hepatitis Group (IAIHG) 03.2017 in : ALIMENT PHARM THER. 45, 5, S. 723-732
  • Liver Int. 2017 May;37(5):694-699. Epub 2016 Nov 19. Antithrombotic treatment with directacting oral anticoagulants in patients with splanchnic vein thrombosis and cirrhosis. De Gottardi A1, Trebicka J2, Klinger C3, Plessier A4, S
  • Reichert MC, Hall RA, Krawczyk M, Lammert F. Genetic determinants of cholangiopathies: Molecular and systems genetics. Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1484-1490. doi: 10.1016/j.bbadis.2017.07.029. Epub 2017 Jul 27. Review. PubMed PMID: 28757171.
  • Jüngst C, Stadlbauer V, Reichert MC, Zimmer V, Weber SN, Ofner-Ziegenfuß L, Voigtländer T, Spindelböck W, Fickert P, Kirchner GI, Lammert F, Lankisch TO, Krawczyk M. NOD2 gene variants confer risk for secondary sclerosing cholangitis in critically ill patients. Sci Rep. 2017 Aug 1;7(1):7026. doi: 10.1038/s41598-017-06268-y. PubMed PMID: 28765628; PubMed Central PMCID: PMC5539147.
  • Krawczyk M, Ligocka J, Ligocki M, Raszeja-Wyszomirska J, Milkiewicz M, Szparecki G, Ilczuk T, Górnicka B, Zieniewicz K, Krawczyk M, Lammert F, Milkiewicz P. Does transient elastography correlate with liver fibrosis in patients with PSC? Laennec score-based analysis of explanted livers. Scand J Gastroenterol. 2017 Dec;52(12):1407-1412. doi: 10.1080/00365521.2017.1370009. Epub 2017 Aug 29. PubMed PMID: 28851259.
  • Kuś A, Arłukowicz-Grabowska M, Szymański K, Wunsch E, Milkiewicz M, Płoski R, Shums Z, Norman GL, Milkiewicz P, Bednarczuk T, Krawczyk M. Genetic Risk Factors for Autoimmune Thyroid Disease might Affect the Susceptibility to and Modulatethe Progression of Primary Biliary Cholangitis. J Gastrointestin Liver Dis. 2017 Sep;26(3):245-252. doi: 10.15403/jgld.2014.1121.263.kus. PubMed PMID: 28922436.
  • Krawczyk M, Lammert F. Search for Genetic Modifiers of PSC: Time to Increase the Number of Needles in the Haystack. Ann Hepatol. 2017 November-December,;16(6):830-831. doi: 10.5604/01.3001.0010.5271. PubMed PMID: 29055915.

2016

  • miR-24 Inhibition Increases Menin Expression and Decreases Cholangiocarcinoma Proliferation. Ehrlich L, Hall C, Venter J, Dostal D, Bernuzzi F, Invernizzi P, Meng F, Trzeciakowski JP, Zhou T, Standeford H, Alpini G, Lairmore TC, Glaser S. Am J Pathol. 2017 Mar;187(3):570-580. doi: 10.1016/j.ajpath.2016.10.021. Epub 2017 Jan 11
  • The "gut microbiota" hypothesis in primary sclerosing cholangitis. Pontecorvi V, Carbone M, Invernizzi P. Ann Transl Med. 2016 Dec;4(24):512. doi: 10.21037/atm.2016.12.43

  • Kelly D, Hartleif S, Verkade HJ, Rajanayagam J, McKiernan P, Mazariegos G, Hübscher S. Late Graft Hepatitis and Fibrosis in Pediatric Liver Allograft Recipients: Current Concepts and Future Developments Reply. Liver Transplantation, 23(3), 405-406. https://doi.org/10.1002/lt.24705

Guidelines

2018

  • European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu; European Association for the Study of the Liver. EASL Clinical Practice Guidelines on nutrition in chronic liver disease. J Hepatol. 2019 Jan;70(1):172-193. doi: 10.1016/j.jhep.2018.06.024. Epub 2018 Aug 23. PubMed PMID: 30144956.

2017

  • EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. - Journal Of hepatology 2017 vol 67: 145-172. "http://www.easl.eu/medias/cpg/Primary%20biliary%20cholangitis/English-report.pdf":http://www.easl.eu/medias/cpg/Primary%20biliary%20cholangitis/English-report.pdf
  • Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline. Aabakken, L., Karlsen, T. H., Albert, J., Arvanitakis, M., Chazouilleres, O., Dumonceau, J-M., Färkkilä, M., Fickert, P., Hirschfield, G. M., Laghi, A., Marzioni, M., Fernandez, M., Pereira, S. P., Pohl, J., Poley, J-W., Ponsioen, C. Y., Schramm, C., Swahn, F., Tringali, A. & Hassan, C. 06.2017 in : ENDOSCOPY. 49, 6, S. 588-608
  • Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. Fawaz R1, Baumann U, Ekong U, Fischler B, Hadzic N, Mack CL, McLin VA, Molleston JP, Neimark E, Ng VL, Karpen SJ. J Pediatr Gastroenterol Nutr. 2017 Jan;64(1):154-168. doi: 10.1097/MPG.0000000000001334.

Conference Proceedings / Presentations

2018

  • Association Franco-Israélienne d Hépato- Gastro-entérologie - Les maladies vasculaires du foie en 2018 : de nouveaux noms et de nouveaux concepts – Paris – Pr Pierre-Emmanuel RAUTOU
  • 7th Symposium Hepatology 2018 - Role of microparticles in portal hypertension – Bern – Pr Pierre-Emmanuel RAUTOU
  • Liver failure in Pediatrics- are children different?. DIVI Intensive Care Meeting, Leipzig Germany, November 2018
  • Management of cholestatic pruritus in Children; GPGE meeting, Freiburg, Germany March 2018
  • Induction of tolerance in living donor transplantation; CPLD meeting Hamburg, November 30, 2018
  • Organ allocation to children, Eurotransplant meeting, Leiden The Netherlands, October 4, 2018
  • Immunosuppression after pediatric liver transplantation- arm or disarm? University of Aachen Medical Center, December 17, 2018.
  • *ERN Rare Liver session at Conference on Pediatric Liver Disease, Hamburg November 29, 2018* 15.00-16.20 ERN RARE liver – Introduction Ekkehard Sturm (Tübingen) Biliary atresia – Qualitiy of care in Europe Claus Petersen (Hannover) Taking care of young adults with chronic liver disease Ansgar Lohse (Hamburg) Transitioning from pediatric to adult services – Perspective of patients and their families Alison Taylor (Birmingham ) Alpha1-antitrypsin deficiency – Understanding the disease helps to improve care for children Mathias Ruiz (Lyon)

2017

  • Ground round session pregnancy and liver disease amsterdam - EASL 2017 - Dr Audrey PAYANCE – Internationale
  • Rare liver diseases in children. DGVS workshop Berlin October 2017, December 2018
  • Acute liver failure in children. GNPI Pediatric Intensive Care Workshop 2017 and 2018, Schloß Reisensburg, Germany.

  • Symposium Medtronic - Paris - Pr Dominique VALLA - Internationale
  • Hepatology meeting Casablanca - Maroc - Pr Dominique VALLA - Internationale
  • The Liver Meeting (AASLD) - États-Unis - Pr Dominique VALLA - Internationale
  • Coagulation in liver disease - Italy - Pr Dominique VALLA - Internationale
  • Israelian association for the study of the liver - Israel - Pr Dominique VALLA - Internationale
  • AISF Update on BCS - Roma - Dr Aurélie PLESSIER - Internationale
  • NCPHT and anticoagulation - Ascona - Dr Aurélie PLESSIER - Internationale
  • Alexion seminary for medical staff- HPN and vascular liver disease – Paris-Dr Aurélie PLESSIER - Internationale
  • Management of bleeding risk related to invasive procedures in NCPHT - 8 Annual Scientific Meeting In Hepatogastroenterology - Egypte - Pr Pierre-Emmanuel RAUTOU - Internationale
  • Invasive methods: evaluation and procedures International liver congress, EASL - The Netherlands - Pr Pierre-Emmanuel RAUTOU - Internationale
  • Endothelial cells in vascular liver diseases - International liver congress EASL - The Netherlands - Pr Pierre Emmanuel RAUTOU - Internationale
  • Diagnostic approach in a patient with thrombosis of the Portal Venous Axis - International liver congress - EASL - The Netherlands - Pr Pierre-Emmanuel RAUTOU - International
  • Management of bleeding risk related to invasive procedures in NCPHT: theory and practice 12th international meeting on therapy in liver diseases. Barcelona – Pr. Pierre-Emmanuel RAUTOU – Internationale
  • Extracellular Vesicles as Mediators of Disease in NCPHT. Coagulation in Liver Diseases meeting - Italy - Pr. Pierre-Emmanuel RAUTOU - Internationale
  • Conference on BCS practical flowchart from diagnosis to treatment – Porto – Dr Aurélie PLESSIER – International
  • European association for the study of the liver (EASL)”. PSD cause or consequence- Paris – Dr Aurélie PLESSIER – International
  • Porto sinusoidal disease : a new entity, SMMAD/AFEF – Tanger – Dr Aurélie PLESSIER – International
  • Club HTP AFEF - Recommandations francophones des maladies vasculaires du foie – Paris – Dr Aurélie PLESSIER
  • ELITA – BCS – Paris – Dr Aurélie PLESSIER
  • Royal College of Physicians of Edinburgh - Splanchnic vein thrombosis – Edimbourg – Pr Dominique VALLA – International
  • Preceptorship de l’Université de Berne - Portal vein thrombosis – Berne – Pr Dominique VALLA – International
  • Journée d’hépatologie de Porto - Portal vein thrombosis and cirrhosis – Porto – Pr Dominique VALLA – International
  • Asian Pacific Association for the Study of the Liver (APASL) - Pregnancy and vascular liver diseases - New Delhi – Pr Pierre-Emmanuel RAUTOU – International
  • Asian Pacific Association for the Study of the Liver (APASL) - Pathophysiology and diagnosis of hypercoagulable state in vascular diseases of liver- New Delhi – Pr Pierre-Emmanuel RAUTOU – International
  • European association for the study of the liver (EASL) - Invasive methods: evaluation and procedures; skill learning center” International liver congress – Paris – Pr Pierre-Emmanuel RAUTOU – International
  • 5th UpDate on Hepatology Course Bucharest - BEST OF EASL: update your clinical practice in vascular diseases of the liver – Bucharest – Pr Pierre-Emmanuel RAUTOU – International
  • 5th Porto Liver Meeting - Systemic atherosclerosis and the liver: who is the culprit and who is the victim? – Porto – Pr Pierre-Emmanuel RAUTOU – International
  • Journées Francophones d’Hépato-gastroentérologie et d’Oncologie digestive - HTP non cirrhotique – Paris – Pr Pierre-Emmanuel RAUTOU
  • Journées Francophones de Radiologie - HTP : physiopathologie, étiologie, conséquences – Paris – Pr Pierre-Emmanuel RAUTOU